ICAM-1 (CD54) Proteins

ICAM-1 (CD54) Human recombinant proteins are validated for use in the following applications: Bioactivity, Neutralization, ELISA standard and Western blot control. These proteins are expressed in CHO cells, E. coli and HEK293 cells. Available Product Grades: Research Use Only. Gibco and... ICAM-1 (CD54) Human recombinant proteins are validated for use in the following applications: Bioactivity, Neutralization, ELISA standard and Western blot control. These proteins are expressed in CHO cells, E. coli and HEK293 cells. Available Product Grades: Research Use Only. Gibco and Invitrogen proteins are some of the most frequently published... ICAM-1 (CD54) Human recombinant proteins are validated for use in the following applications: Bioactivity, Neutralization, ELISA standard and Western blot control. These proteins are expressed in CHO cells, E. coli and HEK293 cells. Available Product Grades: Research Use Only. Gibco and Invitrogen proteins are some of the most frequently published proteins. ICAM-1 (CD54) Protein have been referenced in 4 publications which can be found in our reference library. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 10 proteins, including biologically active options. Not finding the exact protein, grade or size needed?... ICAM-1 (CD54) Human recombinant proteins are validated for use in the following applications: Bioactivity, Neutralization, ELISA standard and Western blot control. These proteins are expressed in CHO cells, E. coli and HEK293 cells. Available Product Grades: Research Use Only. Gibco and Invitrogen proteins are some of the most frequently published proteins. ICAM-1 (CD54) Protein have been referenced in 4 publications which can be found in our reference library. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 10 proteins, including biologically active options. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.

Synonyms

BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells

ICAM-1 (CD54) Proteins

Protein Information

Synonyms

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